LET'S CONNECT
Biomedical Engineering & Clinical Data Science

PATENTS & INNOVATIONS

Bridging clinical nephrology, non-invasive biosensors, predictive artificial intelligence, and mobile health software to make precision renal care universally accessible.

GRANTED
Indian Patent
App: 202641009704
35+
Peer-Reviewed
Scientific Papers
IIIT-B
AI & Data Science
Diagnostics Lead
NEPHRON
Play Store Diet App
World Kidney Day 2025
OFFICIALLY GRANTED INDIAN PATENT • 2026

URINE SODIUM BIOSENSOR (APP NO: 202641009704)

Dietary salt excess is the silent catalyst of hypertension, stroke, and progressive end-stage kidney failure. Until now, accurate 24-hour sodium monitoring required cumbersome all-day urine collections that over 80% of patients failed to complete accurately.

Dr. Ilangovan engineered a microfluidic biosensor coupled with mathematical algorithms that calculates true 24-hour sodium excretion from a single, instant spot urine test. This invention won the prestigious TANKER Award from the Indian Society of Nephrology and was officially granted an Indian Patent in 2026.

Urine Sodium Biosensor Device
Methodology
Microfluidic Spot Sensor
Computational Nephrology

DIGITAL HEALTH & AI DIAGNOSTICS

Deploying software algorithms, mobile health applications, and clinical predictive models to empower patients and assist kidney clinicians.

GOOGLE PLAY STORE

NEPHRON Kidney Diet App

Launched on World Kidney Day (March 13, 2025), this personalized Android application dynamically computes kidney-safe culinary choices based on stage of CKD, eGFR, potassium, acidosis, and diabetes.

  • ✓ Replaces restrictive generic charts with tailored recipes
  • ✓ Real-time potassium and phosphorus risk alerts
  • ✓ Integrated fluid tracking for hemodialysis patients
  • ✓ Available publicly for global patient empowerment
View on Google Play Store →
CLINICAL PORTAL

Transplant Workup Platform

A comprehensive web decision-support system built to streamline pre-transplant donor-recipient immunological workup, HLA antibody risk stratification, and desensitization protocol design.

  • ✓ Automated immunological crossmatch evaluation
  • ✓ HLA mismatch risk stratification calculator
  • ✓ Standardized multi-center donor evaluation workflow
  • ✓ Deployed at transplantworkup.com for clinical teams
Visit Transplant Workup →
DATA SCIENCE & ML

AI-Driven Diagnostic Software

Developed in collaboration with IIIT Bangalore, this machine learning algorithm accurately flags asymptomatic urinary tract infections in high-risk pregnant women using basic routine test variables.

  • ✓ Bypasses 48-hour urine culture delay for immediate safe initiation
  • ✓ Validated against gold-standard microbiological cultures
  • ✓ IIIT Bangalore Data Science Credential: CDS1930028
  • ✓ Published in peer-reviewed biomedical engineering literature
Credential: IIIT-B CDS1930028
Academic Research Output

LANDMARK SCIENTIFIC PUBLICATIONS (35+)

Rigorous clinical trials, randomized controlled studies, and peer-reviewed nephrology papers published across leading international journals.

NUTRIENTS (2022) • IMPACT FACTOR 5.9 Multicenter RCT

Enzobiotics — A novel therapy for the elimination of uremic toxins in patients with CKD (EETOX study): A multicenter double-blind randomized controlled trial.

Saxena A, Srinivasa S, Veerappan I, Jacob C, Mahaldar A, Gupta A, et al. Nutrients. 2022; 14(18): 3804.

KIDNEY INTERNATIONAL REPORTS (2020) Bansal Oration Trial

Individualised cool dialysis alters the Endothelin-1 to Nitric Oxide ratio and improves intradialytic hypertension.

Veerappan I, Chandel V, Sethuraman R. Kidney Int Rep. 2020; 5(3): S304.

INDIAN JOURNAL OF NEPHROLOGY (2019) Hemodynamic Study

Effect of isothermic dialysis on intradialytic hypertension.

Veerappan I, Thiruvenkadam G, Abraham G, Dasari BR, Rajagopal A. Indian J Nephrol. 2019; 29(5): 317-23.

INDIAN JOURNAL OF TRANSPLANTATION (2022) Renal Transplant Protocol

Comparison of efficacy and safety between rabbit anti-thymocyte globulin and anti-T lymphocyte globulin in kidney only transplantation.

Selva Kumar SS, Veerappan I, Sethuraman R, Chakravarthy T, et al. Indian J Transplant. 2022.

THERAPEUTIC APHERESIS AND DIALYSIS (2022) Extracorporeal Therapy

Effect of intestinal dialysis using polyethylene glycol on fluid balance and thirst in maintenance hemodialysis patients.

Bhuwania P, Veerappan I, Sethuraman R, Rajgopal A. Ther Apher Dial. 2022; 26(2): 398-408.